Nuclear Hematology
نویسنده
چکیده
(p. 97) in which sodium-depleted rats no longer corrected their negative sodium balance by drinking hypertonic saline after ventromedial nucleus lesions. However, the reader is frustrated by lack of any citation of this work in the bibliography. A valuable and critical review of sodium "appetite" studies is presented in this chapter. The section dealing with peptides from the diencephalon or kidney and their action upon water and electrolyte metabolism is well done. When the author passes on to the relation between water and osmotic balance and food intake, the reader is again struck by the paucity of citation of more recent literature. Little work is reviewed that has been done since the early 1950's. The description on page 170 of experiments in which oxytocin or other peptidyl derivatives infused into chloralose-anesthetized animals resulted in rapid awakening are of particular interest to experimental neurologists. However, one could not agree with the simplified view the author takes of the mechanisms of consciousness when he states that this phenomenon can be produced only as a result of activation of "the diencephalic reticular system." Aside from the sections reviewing the regulation of electrolyte intake, the effects of peptides upon water and electrolyte metabolism, the monograph falls short. If the arguments or interpretations that the author proposes are to be convincing, they must be more rigorous and based upon a more extensive review of the literature.
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ورودعنوان ژورنال:
- The Yale Journal of Biology and Medicine
دوره 39 شماره
صفحات -
تاریخ انتشار 1966